Glow in the dark tumors: it sounds like something out of a sci-fi novel, but actually, the use of a dye that glows under infrared light could drastically improve surgical outcomes for cancer patients and reduce the chance of recurrence.
Often, surgical removal is difficult because doctors can’t always be certain of the location of tumor margins. So researchers tested a dye that is already approved by the FDA and glows green under infrared light.This dye concentrates in cancerous tissues, so when the surgeon shines an infrared light on the surgical area, the tumor cells will glow.
Working with mice, they found that this dye helped them ‘highlight’ tumors before they were visible to the naked eye. Veterinarians then used the dye on several pet dogs with lung cancer before surgery, and found that it improved visibility of the tumors.
After proving the effectiveness of this dye in mice and dogs, human clinical trials were approved, and the dye actually helped doctors visualize human tumors as well as diagnose patients more accurately. This is a great example of research progressing from bench to bedside. Read more about it here: