This is incredible- researchers at the University of Ottawa have developed a therapy that can kill human blood cancer cells in the laboratory AND successfully eradicate leukemia in mice with few side effects.
Currently, “replicating viruses” are often used for treating leukemia. These are viruses that have been tailored to target cancer cells- but the problem is that the viruses will then replicate and cause viral infections.
UV light was used to transform replicating viruses into non-replicating particles that can still enter cancer cells, kill them, and stimulate a strong immune response from the body. This new therapy is very safe at high doses, worked well in the mouse model, and also killed leukemia cells in the laboratory in blood samples from human leukemia patients who had not responded to other treatments.
Normal blood cells were unharmed. In the mouse studies, 80% of the mice who underwent this treatment had higher survival rates, 60% were CURED, and all untreated died within 20 days.
Steps will now be taken to calculate dosages needed for human patients- and if this works, there may be real hope for leukemia patients who haven’t responded to treatment as well as patients who must face the debilitating side effects of current cancer therapies.
Have you had any personal experiences with side effects of leukemia therapies?