Tag Archives: cholestyramine

Family dog saved… by rats!

Levi by Lake JacksonAnnabelle, an Australian Shepherd, was spending time with her family at a Montana lake when disaster struck. As they were heading to the shore, Annabelle jumped out of the boat, swam to shore, and in the process of drying off, she licked her wet fur. This is a pretty normal thing for a dog to do, but this time, it almost turned deadly. 

When fertilizers or other organic nutrients enter lakes and streams, it can result in large blooms of blue-green algae called cyanobacteria. Unfortunately, cyanobacteria living in this particular lake had produced a liver toxin called microcystin, and after Annabelle ingested it, she quickly became sick. Her veterinarian rushed to find something that could save her life.

Cholestyramine, a drug that had worked against this type of poisoning in rats, was suggested. It had never been tested in dogs, but Annabelle had no other option- without some type of treatment, she would die.

After her vet administered the drug, Annabelle started improving the very next day! Researchers hope that results in one species will give them an indication of the way other species will react to the same drug or treatment. Fortunately for Annabelle, this was a case where rats and dogs had the same type of reaction to this particular treatment, and without those rats, Annabelle wouldn’t have survived. Read more about it here:

http://www.the-scientist.com/?articles.view/articleNo/39760/title/Dog-s-Worst-Friend/