Tag Archives: doberman

Albino Doberman Pinschers: genetic culprit identified!

doi:10.1371/journal.pone.0092127.g001

doi:10.1371/journal.pone.0092127.g001

Researchers at Michigan State University have finally identified the genetic mutation that causes albinism in Doberman Pinschers. The same gene can also cause a form of albinism in humans. This gene mutation results in a missing protein that is necessary for cells to be pigmented. And unfortunately, both dogs and humans with albinism can experience sun sensitivity and are at a higher risk for skin tumors. But identifying the genetic culprit behind the condition is a big deal!

This gene can be carried without being expressed, which means that a dog that doesn’t exhibit albinism could pass the gene to its offspring. This research could help improve Doberman breeding programs by identifying the genes to select away from. Healthier dogs are good for everyone!

Humans and animals are more similar than you may think when it comes to genes, diseases, and illnesses. In this particular case, the genetic variance that causes albinism is similar in dogs and in humans. It’s possible that this knowledge could allow researchers to look at possible ways of preventing skin tumors in dogs with albinism, and then translate those results into treatments for humans!

http://msutoday.msu.edu/news/2014/mans-best-friend-shares-similar-albino-gene/

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0092127