Tag Archives: medication

New drug reduces blood clots without increasing bleeding risk

iStock_000000529518SmallIt’s pretty likely that you’ve injured yourself at some point or another and experienced a break in your skin that caused bleeding. Skinned knees, paper cuts, hangnails- we’ve all been there. Initially, these injuries can bleed quite a bit, but after a few minutes the bleeding slows and eventually stops.

This is a normal defense mechanism- kind of like your body’s version of a Band-Aid. Platelets clump together to form clots over injuries in order to slow the bleeding and protect your body. But if blood clots form inside veins or arteries, they can slow or even stop blood flow to vital parts of the body and cause serious damage, including heart attacks and strokes.

To prevent or treat blood clots, at-risk patients are usually given blood-thinning drugs. However, these oral medications can spread throughout the body, so the risk of bleeding is also increased.

However, new research could change that. A new drug has proven to be effective in reducing blood clots in dogs and mice without increasing the risk of bleeding! The enzyme in this drug regulates platelet clumping, and it can be injected near the blood clot to work in the desired area without causing unwanted bleeding in other locations.

This type of drug could make a huge difference to patients currently taking blood thinners. The next steps will likely include human trials to determine if results in animals are an indication of the drug’s chances for success in humans. Read more about it here:

http://www.newscientist.com/article/dn26033-targeted-clotbusting-drug-wont-boost-bleeding-risk.html#.U-q-0fldWSp

Pregnant women and narcotics- not a good combination

Pregnant woman with tabletsPregnant women learn pretty quickly that there are long lists of things they’re not supposed to do. Smoking cigarettes, eating sushi, drinking alcohol, and skydiving are out- but why are so many pregnant women taking narcotics?

From 2007 to 2011, each year, over 12% of pregnant women were prescribed opioid painkillers. And unfortunately, the effects on the developing fetus aren’t understood very well. Studies in animals are critical to the understanding of the effects of certain drugs on fetuses, and hopefully, it’s not too late. It is known that the chances of neural tube defects are increased if opioids are used during early pregnancy, and addiction in newborns is a potential problem when opioids are using during late pregnancy.

Regardless, a large number of doctors are commonly prescribing opioids to their pregnant patients. There are always cases where the benefits of medications outweigh the potential risks, but expecting moms should always make sure they’re looking out for their little ones! Before taking medications during pregnancy- especially medications with unknown risks to unborn children- talk to your doctor and do some research for yourself. Definitely stay away from skydiving, but also know that narcotics could be much more dangerous than you might think!

http://www.nytimes.com/2014/04/15/science/surge-in-prescriptions-for-opioid-painkillers-for-pregnant-women.html?rref=science&module=Ribbon&version=context&region=Header&action=click&contentCollection=Science&pgtype=article&_r=0

Are there animals in YOUR medicine cabinet?

Dog and pills.How have animals helped YOU today? If you’re not familiar with research, you might not have any idea. But did you know that most of our medical advances wouldn’t have been possible without animals? It’s amazing to learn about the ways they’ve helped us!

Antibiotic ointment, aspirin, cold medicines, penicillin, anti-depressants, blood pressure and cholesterol medications, insulin, anti-coagulants, anesthesia, HIV drugs, chemotherapy, dialysis, CT scans, MRIs, prosthetics, organ transplants, and thousands of other medications and procedures were developed and determined to be safe for your use, thanks to dedicated researchers and the animals they work with.

The list goes on. I will guarantee that every person reading this has benefited from at least some of these advances. What’s more, I’ll bet your pets have benefited as well! And that’s a wonderful thing! Think of the symptoms we can alleviate due to medications, the life-threatening emergencies that we can SURVIVE, and the illnesses that our children may never get, thanks to vaccines. Polio, measles, cervical cancer, rabies, chicken pox, whooping cough, tetanus, Hepatitis B- and that’s just the beginning of the list!

EMBRACE it. Be thankful for it. The next time you reach into your medicine cabinet, take a minute to think about the scientific advances that led to the development of the medication that’s about to help you!

http://news.discovery.com/animals/animals-in-your-medicine-cabinet-photos-140204.htm

http://fbresearch.org/wp-content/uploads/2013/07/AADflyer-hires.pdf

No more eye drops for glaucoma patients?

Water EyeGlaucoma medication delivered through a contact lens is closer than you might think! About six weeks ago, I wrote about an article discussing the development of this type of lens through animal studies. Read about it here. And now, it looks like a Phase I clinical trial in humans could begin in as little as a year!

In animal studies, these contacts were able to deliver the proper amount of medication consistently and safely over the course of a month. Staying on a medication regimen can be difficult- I’m sure you’ve had a prescription to follow and you’ve missed a pill or two. Keeping up with eye drops is often a challenge for glaucoma patients, because they don’t relieve symptoms. The drops can prevent vision from worsening, but when you don’t have immediate relief from your medication, there’s not as much motivation to stay consistent. The novel design of this lens is pretty cool, and could make a huge difference for patients. Stay tuned- we’ll see what happens in clinical trials!

http://news.yahoo.com/no-more-eye-drops-contact-lens-protoype-delivers-135443434.html