Tag Archives: motivation

Chronic pain sufferers: emotional effects, explained

girl sits in a depression on the floor near the wallPeople suffering from chronic pain often have to deal with depression and lack of motivation. It can be difficult to explain to friends and family who say “Just get out and DO something… it will make you feel better!” But now, there’s some science behind the lack of motivation felt by chronic pain sufferers.

Chronic pain, as debilitating as it may be, actually has a purpose. It serves to limit your behavior in such a way as to promote healing and prevent further injuries. And in the process of preventing you from further damage, chronic pain may actually rewire your brain in a way that decreases your motivation.

Researchers found that mice with chronic pain showed decreased motivation, even when they were given painkillers. They looked at a specific area in the brain associated with pain and motivation and found that nerve cells weren’t firing properly. They found that a specific chemical, called galanin, was the key. When galanin receptors were inactivated in this area, neurons began firing properly, and injured mice showed similar motivation to control mice.

Could treatments targeting galanin receptors change brain currents in such a way as to alleviate the lack of motivation that many HUMAN chronic pain sufferers feel? The emotional effects of chronic pain are often just as draining as the physical effects, and this research could bring hope to chronic pain sufferers. Read more about it here:

http://news.yahoo.com/chronic-pain-makes-mice-lazy-153242900.html