Tag Archives: options

Infertility hope: Uterus transplant results in a healthy baby boy

pixabay baby holding dad's fingerInfertility is a heartbreaking problem that many women and couples face. There’s nothing worse than wanting a baby and being told that it will never happen, or being given the “one in a million” speech. And while there have been many advances in medicine that have helped women overcome the diagnosis of “infertility,” recent news of womb transplant success gives us a new reason to be optimistic!

For women who were born without a uterus (this affects about 1 in 5000 women worldwide) or have lost theirs to cancer, becoming pregnant doesn’t even seem like an option. But in September, all that changed when baby Vincent was born. Vincent’s mother was one of nine patients who had undergone a uterine transplant over the last two years in this particular study. Out of those nine patients, Vincent’s mom was the first to deliver her baby, and six others are currently pregnant.

While several countries may now start their own womb transplant programs, this is unlikely to become a commonplace technique, as it is expensive and risky. Patients must remain on anti-rejection medication to prevent their bodies from rejecting the transplanted uterus. After birth, the uterus would need be removed to prevent long-term health effects from anti-rejection drugs. But it’s still an incredible advance, and women who had no hope of becoming pregnant may now have a chance.

None of this would have been possible without dedicated researchers worldwide and the animal models that have contributed to the understanding and application of this science. Surgical techniques and anti-rejection drugs have progressed to the point of actually allowing a woman without a uterus to undergo a successful transplant and give birth to healthy baby- and that’s amazing! Read more about it here.

New “mouse trap” for cancer cells could revolutionize glioblastoma treatment!

3d rendered illustration - brain tumorGlioblastoma is an aggressive form of brain cancer that can be difficult to treat. The tumors are often located in inaccessible areas, making surgery impossible. So researchers in Atlanta got creative and figured out a way to make the cancer cells more accessible. And their technique is not unlike the concept of a mouse trap- but for this one, rats helped figure it out!

Glioblastoma cells migrate along nerves and blood vessels. And researchers used that information to their advantage by creating a small rod that mimics the shape of these nerves and blood vessels. Through animal studies in rats, they’ve shown that the cancer cells then ‘take the bait’ and migrate along this rod. At the end of the rod, the cells are met with a cancer-killing drug. So instead of delivering drugs to the tumor, the tumor comes to the drug!

This could make a huge difference for patients with inoperable tumors. Not only could this cancer cell “mouse trap” lure cells into an area that would be easier for doctors to access, but it could also work by shrinking slow-growing tumors to the point where they wouldn’t be able to do as much damage. Let’s hope that this treatment makes its way into human trials quickly!

http://www.newscientist.com/article/dn25063-fishing-rod-reels-brain-tumour-cells-to-their-death.html#.UwaZBlMo6P9