Tag Archives: platelet

New drug reduces blood clots without increasing bleeding risk

iStock_000000529518SmallIt’s pretty likely that you’ve injured yourself at some point or another and experienced a break in your skin that caused bleeding. Skinned knees, paper cuts, hangnails- we’ve all been there. Initially, these injuries can bleed quite a bit, but after a few minutes the bleeding slows and eventually stops.

This is a normal defense mechanism- kind of like your body’s version of a Band-Aid. Platelets clump together to form clots over injuries in order to slow the bleeding and protect your body. But if blood clots form inside veins or arteries, they can slow or even stop blood flow to vital parts of the body and cause serious damage, including heart attacks and strokes.

To prevent or treat blood clots, at-risk patients are usually given blood-thinning drugs. However, these oral medications can spread throughout the body, so the risk of bleeding is also increased.

However, new research could change that. A new drug has proven to be effective in reducing blood clots in dogs and mice without increasing the risk of bleeding! The enzyme in this drug regulates platelet clumping, and it can be injected near the blood clot to work in the desired area without causing unwanted bleeding in other locations.

This type of drug could make a huge difference to patients currently taking blood thinners. The next steps will likely include human trials to determine if results in animals are an indication of the drug’s chances for success in humans. Read more about it here:

http://www.newscientist.com/article/dn26033-targeted-clotbusting-drug-wont-boost-bleeding-risk.html#.U-q-0fldWSp