Medical advances over the last several decades have resulted in implantable devices that can improve the quality of human and animal lives. The pacemaker and neurostimulator are two of those devices, and with the help of rabbits, researchers are on their way to making some amazing improvements!
When a patient has one of these devices implanted, it’s understood that they will need follow-up surgeries at certain intervals to replace the battery. Pacemaker, neurostimulator, and spinal cord stimulator batteries last, on average, 5-10 years. But recently, researchers have been able to regulate a rabbit’s heart with a pacemaker that operates off wireless energy! This specific implant is only 3mm long. You can imagine the reduced recovery time after a surgery to implant something this size!
While some doctors are skeptical of life-supporting devices relying on external power, researchers are working to adapt this technology for other types of implants as well. Neurostimulator and spinal cord stimulator batteries tend to be about half the size and thickness of a deck of cards, and often, patients experience a good amount of pain at the battery implantation site. Eliminating the need for a battery for these units could make a huge difference for patients- let’s hope that this technology proves successful!
Do YOU have a battery-powered implant? If so, I’d love to hear your thoughts- do you think this technology will help you?
Horses and rabbits can help improve outcomes for human patients receiving bone marrow transplants. Wait- horses and rabbits? Yes!
Bone marrow transplants involve harvesting stem cells from the bone marrow of a healthy person and transplanting them into a patient with certain cancers or blood disorders- leukemia, aplastic anemia, and sickle cell disease, to name a few. Harvesting stem cells from a relative usually has the best outcome, but that’s not always possible. A full sibling only has about a 25% chance of being a match, so most patients find an unrelated match through the bone marrow registry. (www.bethematch.org) Finding a way to improve the outcome for unrelated matches is always a goal in research- and this is where horses and rabbits come in!
Researchers inject human T-cells into a rabbit or a horse. Then, the animal’s immune system kills the T-cells and their bodies create antibodies. These antibodies are then removed and given to human patients- and they then kill the patient’s T-cells, reducing the risk of rejection!
Horse or rabbit anti-thymocyte globulin (ATG) has been used to prevent organ rejection in transplant patients as well as in the treatment of aplastic anemia. Talk about animals helping people!