Tag Archives: women

Surprise, surprise… Viagara efficacy is gender-dependent

iStock_000000357228SmallAlmost 30 years ago, scientists started developing a drug to treat heart failure. They were looking for a drug that would vasodilate arteries, lower blood pressure, and reduce strain on the heart. In clinical trials to determine safety, male participants reported some unexpected side effects… you get the picture. Based on these side effects, researchers switched gears, and Viagara proved to be a very successful drug in the treatment of erectile dysfunction.

It’s no stretch to see what Viagara has done for men. But as doctors now reconsider the drug as a treatment for heart failure, new research shows that taking gender into consideration is really important. By working with a mouse model that mimics heart failure, researchers looked at the difference between females with different estrogen levels. They found that the hormone estrogen affects the potential benefits of the drug. Based on this new research, it seems that the drug only benefits female mice with higher estrogen levels.

The connection between the drug and estrogen levels shouldn’t be ignored. Hopefully this research will result in better gender-specific treatment strategies, and maybe women will get to benefit from Viagara in a completely different way! Read more here:

http://www.hopkinsmedicine.org/news/media/releases/gender_differences_stand_out_in_measuring_impact_of_viagra_as_therapy_for_heart_failure

Why “Not tonight, I have a headache…” is never the case with men

iStock_000016171517SmallIn yet another example of the similarities between mice and men, researchers have found that males of the mouse species aren’t very likely to turn down sex, even when they’re not feeling that great. On the other hand, feeling under the weather definitely affects a female mouse’s sex drive. When experiencing pain, female mice had much less sexual motivation than usual. But when males were experiencing pain, it didn’t have any effect on the frequency of sexual behaviors displayed.

Sounds pretty similar to a lot of human relationships. The husband of a friend of mine was in the emergency room, waiting for x-rays on his broken ankle, but still suggested that she draw the curtains so they could have a little fun. She thought he was crazy; he thought it was a valid option.

While it’s too early to draw conclusions about complex human behavior from one mouse study, the results do suggest that sexual repression in females may be more biological than emotional in some cases. Could this be evolution at work? Interesting. What are your thoughts?

http://news.sciencemag.org/brain-behavior/2014/04/pain-no-deterrent-male-libido?rss=1